Immunoglobulin G4-related kidney diseases: An updated review
نویسندگان
چکیده
منابع مشابه
Immunoglobulin G4-related kidney diseases: An updated review
This review will encompass definition, pathogenesis, renal clinical manifestations and treatment of immunoglobulin G4-related diseases (IgG4-RDs). IgG4-RD is a recently recognized clinical entity that often involves multiple organs and is characterized by high levels of serum immunoglobulins G4, dense infiltration of IgG4+ cells and storiform fibrosis. Cellular immunity, particularly T-cell med...
متن کاملImmunoglobulin G4 and related diseases.
i mmunoglobulins, produced by plasma cells, are the effector arm of the humoral immune system [1]. Each immunoglobulin consists of two identical heavy chains (α, β, γ, δ or ε – all encoded by chromosome 14) and two identical light chains (either κ or λ, encoded by chromosome 2 and 22, respectively) [2]. The immunoglobulins have constant (C) regions (similar within the same isotype) and variable...
متن کاملImmunoglobulin G4-Related Thyroid Diseases.
Immunoglobulin G4-related disease (IgG4-RD) is a new disease category involving many organ systems, including the endocrine system in general and the thyroid in particular. Since an initial association was made between hypothyroidism and autoimmune (IgG4-related) pancreatitis, more forms of IgG4-related thyroid disease (IgG4-RTD) have been recognized. Four subcategories of IgG4-RTD have so far ...
متن کاملImmunoglobulin G4-related kidney disease: Pathogenesis, diagnosis, and treatment
Immunoglobulin G4-related disease (IgG4-RD) is a recently recognized clinical entity that often involves multiple organs; it is characterized by high levels of serum immunoglobulin G4 (IgG4), dense infiltration of IgG4+ cells, and storiform fibrosis. Cellular immunity, particularly T cell-mediated immunity, has been implicated in the pathogenesis of IgG4-RD. The most frequent renal manifestatio...
متن کاملImmunoglobulin G4-related diseases in the head and neck: a systematic review
BACKGROUND Immunoglobulin G4 related disease (IgG4-RD) is a poorly understood chronic inflammatory disorder affecting the middle-aged and elderly that can present to the otolaryngologist. We aim to summarize the current literature regarding the manifestations and management of IgG4-RD in the head and neck. METHODS Pubmed and EMBASE were searched using the term relevant search algorithm utiliz...
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ژورنال
عنوان ژورنال: World Journal of Nephrology
سال: 2018
ISSN: 2220-6124
DOI: 10.5527/wjn.v7.i1.29